Whether a placebo actually has clinical effects against specific pathologies/symptoms is controversial. From the viewpoint of scientifically evaluating a pharmaceutical treatment, it doesn't matter. If there is no measurable difference in effect (on a specific condition) between a isotonic saline solution and a solution of medicine X, why should you (or your health insurance plan) pay for that solution of medicine X? If medicine X is measurably worse (on a specific condition) than that isotonic saline solution, shouldn't it be malpractice to use it (on that specific condition)?
Obviously, one's choice of religion and/or philosophy will seriously affect what questions one would subject to science. Red China, for instance, has a much easier time scientifically investigating applications of acupressure and acupuncture than the United States.
Disasters can happen when something designed using science is abused by operators who are oblivious to the consequences of flouting the design basis. An example is the Chernoybl reactor meltdown/explosion (1981, Ukraine -- the Soviet Union was the government in effect then). This happened because the plant supervisor deliberately, with reasonable understanding of what could happen, ran the reactor without coolant in order to keep his job.
A more recent example (Japan, 1999 or 2000), again from the nuclear power industry, happened when a nuclear power plant holding company doctored its safety manuals to authorize the direct mixing (by hand) of uranium oxide solutions with insufficient safety factors in quantity. That is, the company directly authorized violating Japanese safety regulations as standard procedure. Three misinstructed workers (following standard procedure), ignorant of what could happen, mixed together a sufficient quantity to cause a momentary uncontrolled fission reaction. This wasn't enough to heat the water -- but the bright blue flash came with a radiation dose sufficient to immediately knock them out. (The least-exposed worker took about 21 sieverts [very roughly 35,000 rem]. 5,000 rem is sufficient to cause cerebrovascular collapse within 24 hours.) The most advanced hospitals in the area were unable to keep the other two workers alive.
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